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Glucosamine is an amino acid sugar that naturally occurs and is synthesized in the body from L-glutamine and glucose. Glucosamine stimulates the manufacture of glycosaminoglycans, which are vital components of the cartilage that is necessary for healthy joints. As we age, we lose our ability to manufacture an adequate amount of glucosamine, and there are no food sources available.
Commercial sources of glucosamine are from the exoskeleton of certain shellfish and are available as glucosamine sulfate, glucosamine hydrochloride, and N-acetyl-glucosamine. The sulfated form may most effectively incorporate sulfur into the cartilage.
Glycosaminoglycans and glycoproteins allow cells in tissues to stay connected . They are needed for the construction and maintenance of virtually all connective tissues and lubricating fluids in the body.
In particular, N-acetyl glucosamine is the final form, which together with glucuronic acid, is polymerized to make the joint lubricant, hyaluronic acid. Chondroitin sulfates provide the structural components of joint cartilage and facilitate the entry of glucosamine into joints. Chondroitin sulfates also inhibit free radical enzymes. Like Glucosamine, chondroitin sulfate attracts water into the cartilage matrix and helps to stimulate the production of cartilage.
Explores the different modalities that have been proven effective for different types of arthritis. A dynamic approach to the prevention and treatment of arthritis.